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Invitrogen
Human HIPK3 (aa 551-636) Control Fragment Recombinant Protein
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Product Details
RP-95200
Species
Expression System
Amino acid sequence
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Conjugate
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83000. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
HIPK3 is a serine/threonine kinase involved in signal transduction, cellular communication, and multidrug resistance of tumors and plays a role in the phosphorylation of FADD. HIPK3 negatively regulates apoptosis by promoting FADD phosphorylation. This kinase enhances androgen receptor-mediated transcription, and may act as a transcriptional corepressor for NK homeodomain transcription factors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Androgen receptor-interacting nuclear protein kinase; ANPK; Fas-interacting serine/threonine-protein kinase; FIST; Homeodomain-interacting protein kinase 3; Homolog of protein kinase YAK1; RP1-8L15.1
Gene Aliases: DYRK6; FIST3; HIPK3; PKY; YAK1
UniProt ID: (Human) Q9H422
Entrez Gene ID: (Human) 10114
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