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Invitrogen
Cynomolgus IL-13 His-tag Recombinant Protein
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Product Details
RP-87946
Species
Expression System
Amino acid sequence
Tag
Molecular weight
Class
Type
Purity
Endotoxin concentration
Activity
Conjugate
Form
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (2222 µL) be added to the vial to prepare a stock solution of 0.45 mg/mL.
Concentration is measured by UV.
Target Information
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: ALRH; ALRH antibody; BHR1; il 13; ILN; Interleukin; interleukin 13; Interleukin13; MGC116786; MGC116788; MGC116789; NC30 antibody; P600 antibody
Entrez Gene ID: (Cynomolgus monkey) 102125887
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