CD10 ELISA Kits

ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for CD10 are available for Human and Mouse which can be quantified in various samples, including plasma, serum, supernatant.

Invitrogen ELISA kits exist in two formats:... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for CD10 are available for Human and Mouse which can be quantified in various samples, including plasma, serum, supernatant.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated.... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for CD10 are available for Human and Mouse which can be quantified in various samples, including plasma, serum, supernatant.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for CD10 are available for Human and Mouse which can be quantified in various samples, including plasma, serum, supernatant.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits are ready-to-use and quality tested for sensitivity, specificity, precision and lot-to-lot consistency.

Target Information

CD10, also known as the Common Acute Lymphocytic Leukemia Antigen (CALLA) and neutral endopeptidase (NEP), is a Zn2+-dependent metallo-peptidase with neutral metalloendopeptidase activity. It is a 100 kDa type II transmembrane glycoprotein encoded by a gene that exists in a single copy of greater than 45 kb. The 5' untranslated region of the CD10 gene is alternatively spliced, resulting in four separate mRNA transcripts, although the coding region remains unaffected by alternative splicing. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils and plays a role in stromal cell-dependent B lymphopoiesis. It is expressed on immature B cells in adult bone marrow, mature B cells in germinal centers, and cells from patients with chronic myelocytic leukemia (CML). Additionally, CD10 is present on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas. Beyond the hematopoietic compartment, CD10 is highly expressed on the brush border of enterocytes and renal tubules and glomeruli, as well as on breast myoepithelial cells, bile canaliculi, and fibroblasts. CD10 cleaves peptides at the amino side of hydrophobic residues, inactivating several biologically active peptides, including endothelin, glucagon, gastrin, neurotensin, bradykinin, enkephalins, substance P, oxytocin, and others. Diseases associated with CD10 dysfunction include spinocerebellar ataxia 43 and Charcot-Marie Tooth Disease, highlighting its significance in both normal physiological processes and disease states.

Synonyms

6030454K05Rik; Atriopeptidase; C85356; CALLA; CD10; CMT2T; common acute lymphoblastic leukemia antigen; common acute lymphocytic leukemia antigen; Enkephalinase; EPN; membrane metallo endopeptidase; membrane metalloendopeptidase; membrane metallo-endopeptidase; membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10); membrane metallo-endopeptidase (neutral endopeptidase/enkephalinase); membrane metallo-endopeptidase variant 1; membrane metallo-endopeptidase variant 2; MME; NEP; neprilysin; neprilysin-390; neprilysin-411; neutral endopeptidase 24.11; SFE; Skin fibroblast elastase

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Invitrogen

Human Neprilysin (MME) ELISA Kit

Invitrogen

Human Neprilysin (MME) ELISA Kit

Sensitivity 0.4 ng/mL

Assay Range 0.41-100 ng/mL

Sample Volume

Plasma

50 µL

Serum

50 µL

Supernatant

100 µL

Time To Result

4 hr 45 min

(1 hr 20 min hands-on)

Price

Cat # EHMME

Invitrogen

Mouse Neprilysin ELISA Kit

Invitrogen

Mouse Neprilysin ELISA Kit

Sensitivity 61 pg/mL

Assay Range 61-15,000 pg/mL

Sample Volume

Serum

50 µL

Plasma

50 µL

Supernatant

50 µL

Time To Result

4 hr 45 min

(1 hr 20 min hands-on)

Price

Cat # EM55RB

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CD10 ELISA Kits

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