BCL-2 ELISA Kits

ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Human BCL-2 can be quantified in various samples, including cell lysate, plasma, serum.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated.... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Human BCL-2 can be quantified in various samples, including cell lysate, plasma, serum.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Human BCL-2 can be quantified in various samples, including cell lysate, plasma, serum.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits... ELISA kits are commonly used to measure soluble biomarkers across a variety of research areas. ELISA kits for Human BCL-2 can be quantified in various samples, including cell lysate, plasma, serum.

Invitrogen ELISA kits exist in two formats: Uncoated and Coated. Uncoated ELISA kits include all the necessary reagents to coat your own plates and run your assay with maximum flexibility. Coated ELISA kits are ready-to-use and quality tested for sensitivity, specificity, precision and lot-to-lot consistency.

Target Information

BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death. The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis. Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2. Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis. Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative. Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends. The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.

Synonyms

Apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50

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Invitrogen

Human BCL-2 ELISA Kit

Invitrogen

Human BCL-2 ELISA Kit

Sensitivity <0.5 ng/mL

Assay Range 0.50-32.0 ng/mL

Sample Volume

Cell Lysate

20 µL

Plasma

20 µL

Serum

20 µL

Time To Result

3 hr 10 min

(1 hr 20 min hands-on)

Price

Cat # BMS244-3

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BCL-2 ELISA Kits

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