Invitrogen
Rat IL-10 ELISA Kit
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Product Specifications
Analytical sensitivity
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Homogenous (no wash)
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Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
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Chromogen
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Detector antibody conjugate
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About This Kit
Rat IL-10 quantitates rat IL-10 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat IL-10.
IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : Il-10, Il10, IL10X
Gene ID : (Rat) 25325
Gene symbol : Il10
Protein Aliases : CSIF, Cytokine synthesis inhibitory factor, H-IL-10, MGC126450, MGC126451, RP11-262N9.1, Interleukin10, il 10, ILN, Interleukin, IL-10, Interleukin-10
UniProt ID (Rat) P29456
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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