Invitrogen
Mouse TWEAK R (CD266/TNFRSF12A) ELISA Kit
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Product Specifications
Analytical sensitivity
Assay range
Sample type/volume
Hands-on time
Time-to-result
Homogenous (no wash)
Interassay CV
Intraassay CV
Instrument
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Contents
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
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Protein name
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Species (tested)
Assay kit format
Detector antibody conjugate
Label or dye
About This Kit
The Mouse TWEAK R (CD266/TNFRSF12A) ELISA quantitates Ms TWEAK R in mouse serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Ms TWEAK R.
Principle of the method
The Mouse TWEAK R solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
Rigorous validation
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
TWEAK is a member of the TNF family and was first described as a weak inducer of apoptosis in demonstrate that this relatively small molecule is a fully transformed cell lines. Recently, a receptor for TWEAK was isolated by expression cloning from a HUVEC cell cDNA library. TweakR is a small protein belonging to TNF receptor super family. TweakR is capable of intiating a proliferative signal by binding to TRAF1, 2, and 3. TweakR mRNA is upregulated during tissue regeneration in the aorta and liver. It may also play a role in vascular cell migration and angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : AI255180, C87282, Fgfrp2, Fn14, HPIP, Tnfrsf12a, TWEAK-R, TweakR
Gene ID : (Mouse) 27279
Gene symbol : Tnfrsf12a
Protein Aliases : CD266, FGF-inducible 14, fibroblast growth factor regulated protein 2, Fibroblast growth factor-inducible immediate-early response protein 14, Fibroblast growth factor-regulated protein 2, Tumor necrosis factor receptor superfamily member 12A, Tweak-receptor, TweakR, type I transmembrane protein Fn14
UniProt ID (Mouse) Q9CR75
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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