Invitrogen
Mouse/Rat OPN ELISA Kit
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Product Specifications
Analytical sensitivity
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Homogenous (no wash)
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Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
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Detector antibody conjugate
Label or dye
About This Kit
Rat OPN quantitates rat OPN in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant rat OPN.
Osteopontin is an arginine-glycine-aspartic acid (RGD)-containing glycoprotein that interacts with integrins and CD44 as major receptors. It is a multifunctional protein involved in bone mineralization, cell adhesion, cell migration, chronic inflammatory disease and transformation. Proteolytic cleavage by thrombin and matrix metalloproteinases close to the integrin-binding Arg-Gly-Asp sequence modulates the function of OPN and its integrin binding properties. Thrombin-cleaved fragments of Osteopontin are overexpressed in malignant glial tumors and provide a molecular niche with survival advantage and provide a novel substrate for plasmin and cathepsin D.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : 2AR, 2b7, Apl-1, BNSP, Bsp, BSPI, Eta, ETA-1, OP, Opn, Opnl, OSP, Ric, Spp-1, Spp1
Gene ID : (Mouse) 20750, (Rat) 25353
Gene symbol : Spp1, Spp1
Protein Aliases : 2AR, 44 kDa bone phosphoprotein, Bone sialoprotein 1, Calcium oxalate crystal growth inhibitor protein, Early T-lymphocyte activation 1 protein, HGNC:11255, MGC110940, immunoglobulin alpha 1 heavy chain constant region fusion protein, urinar, secreted phosphoprotein 1 (osteopontin bone sialoprotein I early T lymphocyte activation 1), Secreted phosphoprotein 1 (SPP1), Bone sialoprotein 1 (BSPI/BSP1), CALPHA1 fusion, Early T lymphocyte activation 1 (ETA1), Minopontin, Osteopontin, osteopontin-like protein, Secreted phosphoprotein 1, Sialoprotein (osteopontin), SPP-1
UniProt ID (Mouse) P10923, (Rat) P08721
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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