Invitrogen
Mouse Mast Cell Protease-6/Mcpt6 ELISA Kit
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Product Specifications
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Homogenous (no wash)
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Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
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Detector antibody conjugate
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About This Kit
Mouse Mast Cell Protease-6/Mcpt6 quantitates mouse Mast Cell Protease-6/Mcpt6 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Mast Cell Protease-6/Mcpt6.
TPSB2 is a protein coding gene. Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : AV011504, Mcp-6, Mcp6, Mcpt6, MMCP-6
Gene ID : (Mouse) 17229
Gene symbol : Tpsb2
Protein Aliases : EC 3.4.21, EC 3.4.21.59, TPS2tryptase beta-2, tryptase beta II, tryptase beta III, tryptase III, Tryptase-C, mast cell protease 6, tryptase beta-2, tryptase-2
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If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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