Invitrogen
Human beta-2 Defensin ELISA Development Kit (TMB), PeproTech®
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Product Specifications
Analytical sensitivity
Assay range
Hands-on time
Time-to-result
Homogenous (no wash)
Instrument
Product size
Contents
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Protein name
Protein family
Species (tested)
Assay kit format
Detector antibody conjugate
Label or dye
About This Kit
900-T172K consists of: 900-T172 (capture antibody, detection antibody, and protein standard), and HRP-17UL (streptavidin HRP-conjugate).
Human beta-2 Defensin TMB ELISA Development Kit contains the key components required for the quantitative measurement of natural and/or recombinanthuman beta-2 Defensin in a sandwich ELISA format. Human beta-2 Defensin TMB ELISA Development Kit contains enough material to assay the target cytokine in at least 1,000 ELISA plate wells.
The TMB ELISA Buffer Kit (Product # 900-T00), sold separately, is recommended to be used in conjunction with this TMB ELISA Development Kit for optimal performance. This buffer kit contains all the necessary components to assay ten 96-well ELISA plates (included) and contains detailed handling instructions.
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : BD-2, DEFB-2, DEFB102, DEFB2, DEFB4, DEFB4A, DEFB4B, HBD-2, SAP1
Gene ID : (Human) 1673
Gene symbol : DEFB4A
Protein Aliases : BD-2, beta defensin 2, beta defensin-2, Beta-defensin 2, Defensin beta 2, Defensin beta2, Defensin-beta2, Defensin beta 4A, Defensin, beta 2, defensin, beta 4, beta 4A, SAP1, Skin-antimicrobial peptide 1
UniProt ID (Human) O15263
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If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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