Invitrogen
Human Trypsin 2/PRSS2 ELISA Kit
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Product Specifications
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Homogenous (no wash)
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Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
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Detector antibody conjugate
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About This Kit
Human Trypsin 2/PRSS2 quantitates human Trypsin 2/PRSS2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Trypsin 2/PRSS2.
This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : PRSS2, TRY2, TRY8, TRYP2
Gene ID : (Human) 5645
Gene symbol : PRSS2
Protein Aliases : Anionic trypsinogen, MGC120175, trypsin Trypsin II, EC 3.4.21, EC 3.4.21.4, MGC111183, MGC120174, protease serine 2 preproprotein, protease, serine, 2 (trypsin 2), Serine protease 2, Trypsin II, Trypsin-2, trypsinogen 2
UniProt ID (Human) P07478
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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