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The Human TROY (TNFRSF19) ELISA quantitates Hu TROY in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu TROY.
Principle of the method
The Human TROY solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
Rigorous validation
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
Tumor necrosis factor receptor superfamily member 19, commonly known as TROY, is a gene located on chromosome 1p36.22 that encodes a member of the tumor necrosis factor receptor (TNFR) superfamily. TROY is expressed in the nervous system, skin, and various tissues, where it plays a role in regulating cell apoptosis, inflammation, and development. As a receptor, TROY interacts with ligands and other signaling molecules to modulate pathways involved in cell survival, differentiation, and immune responses. In the context of the nervous system, TROY has been implicated in axonal outgrowth and regeneration, particularly influencing signaling pathways related to neural development and repair. Additionally, TROY has been studied in cancer research due to its potential role in tumor growth and progression, making it a candidate for therapeutic targeting. Its involvement in diverse biological processes highlights its significance in maintaining cellular homeostasis and its potential as a therapeutic target in neurobiology and oncology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Gene aliases : TAJ, TAJ-alpha, TNFRSF19, TRADE, TROY, UNQ1888/PRO4333
Gene ID : (Human) 55504
Gene symbol : TNFRSF19
Protein Aliases : Toxicity and JNK inducer, TRADE, Tumor necrosis factor receptor superfamily member 19, tumor necrosis factor receptor superfamily, member 19
UniProt ID (Human) Q9NS68
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