Invitrogen
Human Semaphorin 6D ELISA Kit
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Product Specifications
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Homogenous (no wash)
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Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
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Adhesive Plate Covers
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Detector antibody conjugate
Label or dye
About This Kit
Human Semaphorin 6D quantitates human Semaphorin 6D in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Semaphorin 6D.
Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphoring domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : KIAA1479, SEMA6D
Gene ID : (Human) 80031
Gene symbol : SEMA6D
Protein Aliases : FLJ11598, KIAA1479FLJ11598, sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, Semaphorin-6D
UniProt ID (Human) Q8NFY4
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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