Invitrogen
Human NKp44 ELISA Kit
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Product Specifications
Analytical sensitivity
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Homogenous (no wash)
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Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
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Chromogen
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Detector antibody conjugate
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About This Kit
Human NKp44 quantitates human NKp44 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human NKp44.
CD336 is also known as NKp44 or NCR2. CD336 is a 44-kDa transmembrane glycoprotein belonging to the natural cytotoxicity receptor (NCR) family and contains an ITIM domain located in the cytoplasmic tail. Expression of CD336 and NK cell activation by the receptor requires association with DAP12, an ITAM-containing transmembrane accessory protein. Once thought to be expressed exclusively on IL-2-activated NK cells and a subset of gamma delta T lymphocytes, studies have shown expression of CD336 on IL-3-stimulated plasmacytoid dendritic cells, alpha beta T cells in the small intestinal epithelium, and T cells in cord blood. CD336 has been shown to be involved in the innate response of activated NK cells against viral infection and tumor cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : CD336, dJ149M18.1, LY95, NCR2, NK-p44, NKP44
Gene ID : (Human) 9436
Gene symbol : NCR2
Protein Aliases : CD336, CD336 antigen, NK-p44dJ149M18.1, natural killer cell receptor, lymphocyte antigen 95 (activating NK-receptor, NK-p44), Lymphocyte antigen 95 homolog, lymphocyte antigen 95 homolog (activating NK-receptor, Natural cytotoxicity triggering receptor 2, Natural killer cell p44-related protein, NK cell activating receptor (NKp44), NK cell-activating receptor, NK-p44
UniProt ID (Human) O95944
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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