Invitrogen
Human/Mouse COCO ELISA Kit
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Product Specifications
Analytical sensitivity
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Homogenous (no wash)
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Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
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Detector antibody conjugate
Label or dye
About This Kit
Human COCO quantitates human COCO in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human COCO.
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : CER2, Cerl-2, CERL2, Cerr2, CKTSF1B3, COCO, CRL2, DAND5, DANTE, Dte, GREM3, SP1
Gene ID : (Human) 199699, (Mouse) 23863
Gene symbol : DAND5, Dand5
Protein Aliases : cerberus 2, cerberus-like 2, Cerberus-like protein 2, Cerl-2, Cysteine knot superfamily 1, BMP antagonist 3, DAN domain family member 5, BMP antagonist, DAN domain family, member 5, dante, FLJ38607, GREM3cerberus 2, MGC126849, CER2CRL2, Cerberus like-2, CKTSF1B3MGC126849, Gremlin-3
UniProt ID (Human) Q8N907, (Mouse) Q76LW6
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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