Invitrogen
Human Cathepsin K ELISA Kit
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Product Specifications
Analytical sensitivity
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Homogenous (no wash)
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Intraassay CV
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Protein name
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Assay kit format
Detector antibody conjugate
Label or dye
About This Kit
The Human Cathepsin K (CTSK) ELISA quantitates Cathepsin K in serum, plasma, and other biological fluids
The Human Cathepsin K solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the binding of the second (detector) antibody to the target on a different epitope from the capture antibody. An antibody conjugated with enzyme binds the formed sandwich. After incubation and washing steps to rid the microplate of unbound substances, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
Rigorous validation:
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : CTS02, CTSK, CTSO, CTSO1, CTSO2, PKND, PYCD
Gene ID : (Human) 1513
Gene symbol : CTSK
Protein Aliases : Cathepsin K, Cathepsin O, cathepsin O1, Cathepsin O2, Cathepsin X, MGC23107
UniProt ID (Human) P43235
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