Invitrogen
Human CRISP-2 ELISA Kit
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Product Specifications
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Homogenous (no wash)
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Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
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Detector antibody conjugate
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About This Kit
Human CRISP-2 quantitates human CRISP-2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CRISP-2.
The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : CRISP-2, CRISP2, CT36, GAPDL5, TPX1, TSP1
Gene ID : (Human) 7180
Gene symbol : CRISP2
Protein Aliases : Cancer/testis antigen 36, CRISP-2, CT36, Cysteine-rich secretory protein 2, glyceraldehyde-3-phosphate dehydrogenase-like 5, MGC111136, OTTHUMP00000016589, testicular tissue protein Li 43, testis specific protein 1 (probe H4-1 p3-1), Testis-specific protein TPX-1
UniProt ID (Human) P16562
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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