Invitrogen
Human CD4 ELISA Kit
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Product Specifications
Analytical sensitivity
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Time-to-result
Homogenous (no wash)
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Contents
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
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Adhesive Plate Covers
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Assay kit format
Detector antibody conjugate
Label or dye
About This Kit
Human CD4 quantitates human CD4 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CD4.
The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : CD4, CD4mut
Gene ID : (Human) 920
Gene symbol : CD4
Protein Aliases : CD4, CD4 antigen (p55), CD4 antigen p55, fCD4, Leu-3, cd4a, CD4 receptor, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
UniProt ID (Human) P01730
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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