Invitrogen
Human CD36/SR-B3 ELISA Kit
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Product Specifications
Analytical sensitivity
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Homogenous (no wash)
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Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
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Adhesive Plate Covers
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Detector antibody conjugate
Label or dye
About This Kit
Human CD36/SR-B3 quantitates human CD36/SR-B3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CD36/SR-B3.
CD36, also known as scavenger receptor class B member 3, is a protein that is expressed on the surface of various cell types, including macrophages, platelets, and adipocytes. It plays a role in lipid metabolism, inflammation, and atherosclerosis, and is involved in the recognition and uptake of various ligands such as oxidized low-density lipoproteins, long-chain fatty acids, and apoptotic cells. CD36 is also implicated in the pathogenesis of malaria. The protein encoded by this gene serves as a receptor for thrombospondin in platelets and various cell lines, and is the fourth major glycoprotein of the platelet surface. It binds to collagen, thrombospondin, anionic phospholipids, and oxidized LDL, and directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. Diseases associated with CD36 include Platelet Glycoprotein IV Deficiency and Coronary Heart Disease 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : BDPLT10, CD36, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3
Gene ID : (Human) 948
Gene symbol : CD36
Protein Aliases : CD36, CD36 antigen (collagen type I receptor, thrombospondin receptor), CD36 molecule (thrombospondin receptor), cluster determinant 36, FAT, Fatty acid translocase, Glycoprotein IIIb, GPIIIB, GPIV, Leukocyte differentiation antigen CD36, PAS IV, PAS-4, PAS-4 protein, Platelet collagen receptor, Platelet glycoprotein 4, Platelet glycoprotein IV, scavenger receptor class B, member 3, SR-B3, Thrombospondin receptor
UniProt ID (Human) P16671
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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