Invitrogen
Human Angiotensinogen ELISA Kit
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Product Specifications
Analytical sensitivity
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Homogenous (no wash)
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Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
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Adhesive Plate Covers
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Detector antibody conjugate
Label or dye
About This Kit
Human Angiotensinogen quantitates human Angiotensinogen in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Angiotensinogen.
The protein encoded by AGT, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : AGT, ANHU, SERPINA8
Gene ID : (Human) 183
Gene symbol : AGT
Protein Aliases : alpha-1 antiproteinase, antitrypsin, angiotensin I, angiotensin II, Angiotensinogen, angiotensinogen (serpin peptidase inhibitor, clade A, member 8), pre-angiotensinogen, serine (or cysteine) proteinase inhibitor, Serpin A8, serpin peptidase inhibitor, member 8
UniProt ID (Human) P01019
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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