Invitrogen
Human ADAMTS4 ELISA Kit
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Product Specifications
Analytical sensitivity
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Homogenous (no wash)
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Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
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Adhesive Plate Covers
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Detector antibody conjugate
Label or dye
About This Kit
Human ADAMTS4 quantitates human ADAMTS4 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ADAMTS4.
This gene encodes a member of the ADAMTS protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : ADAMTS-2, ADAMTS-4, ADAMTS4, ADMP-1, KIAA0688, UNQ769/PRO1563
Gene ID : (Human) 9507
Gene symbol : ADAMTS4
Protein Aliases : A disintegrin and metalloproteinase with thrombospondin motifs 4, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4, ADAM metallopeptidase with thrombospondin type 1 motif, ADAM-TS 4, ADAM-TS4, ADMP-1, Aggrecanase 1, metalloendopeptidases, a disintegrin and metalloproteinase, ADAM, ADAMs, Aggrecanase-1
UniProt ID (Human) O75173
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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