Invitrogen
Feline IL-12p40 ELISA Kit
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Product Specifications
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Homogenous (no wash)
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Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
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Detector antibody conjugate
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About This Kit
Feline IL-12p40 quantitates feline IL-12p40 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant feline IL-12p40.
IL12B (IL-12 p40) encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kDa cytokine receptor like subunit encoded by this gene, and a 35 kDa subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Gene aliases : IL-12.p40, IL12B
Gene ID : (Cat) 768273
Gene symbol : IL12B
Protein Aliases : CLMF p35, IL-12 subunit p35, IL12A, IL12 p40, ILN, Interleukin, Interleukin 12, Interleukin12, il 12, IL-12A, NKSF1, RP23-388G23.1, CLMF p40, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, IL-12B, interleukin 12 p40 subunit, interleukin-12 beta chain, interleukin-12 p40 chain, Interleukin-12 subunit beta
UniProt ID (Cat) O02744
Performance Guarantee
If an Invitrogen™ immunoassay doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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