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Fabgennix
proBNP Polyclonal Antibody
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Product Details
PBNP-101AP
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Target Information
In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa "signal" peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: BNP32; Brain natriuretic factor; Brain natriuretic factor prohormone; brain natriuretic peptide; brain type natriuretic peptide; Gamma-brain natriuretic peptide; Iso-ANP; natriuretic peptide precursor B; natriuretic peptide precursor type B; Natriuretic peptides B; natriuretic protein; NTproBNP; preproBNP; type-B natriuretic factor
Gene Aliases: AA408272; BNF; BNP; NPPB
UniProt ID: (Human) P16860, (Rat) P13205, (Mouse) P40753
Entrez Gene ID: (Human) 4879, (Rat) 25105, (Mouse) 18158
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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