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Invitrogen
pro-Brain Natriuretic Peptide Monoclonal Antibody (11D1)
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FIGURE: 1 / 2
pro-Brain Natriuretic Peptide Antibody (MA1-20584) in WB
Product Details
MA1-20584
Species Reactivity
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Product Specific Information
MA1-20584 detects proBNP in human samples.
Target Information
In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa "signal" peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: BNP32; Brain natriuretic factor prohormone; brain type natriuretic peptide; Gamma-brain natriuretic peptide; Iso-ANP; natriuretic peptide precursor B; Natriuretic peptides B; natriuretic protein; NTproBNP; preproBNP
Gene Aliases: BNP; NPPB
UniProt ID: (Human) P16860
Entrez Gene ID: (Human) 4879
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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