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Invitrogen
eIF4A2 Polyclonal Antibody
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FIGURE: 1 / 8
eIF4A2 Antibody (PA5-79195) in ICC/IF
Product Details
PA5-79195
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
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Concentration
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Storage buffer
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RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human HepG2 whole cell, human U251 whole cell, human SiHa whole cell, human K562 whole cell, rat brain tissue, rat lung tissue, mouse brain tissue, mouse lung tissue . IHC: mouse spleen tissue, rat intestine tissue, human mammary cancer tissue. ICC/IF: A431 cell. Flow: SiHa cell.
Target Information
eIF4A2 is a 407 amino acid ATP-dependent RNA helicase belonging to the DEAD box helicase family. It contains one helicase ATP-binding domain and a helicase C-terminal domain. eIF4A2, a subunit of the eIF4F complex, acts as a protein-synthesis initiation factor and thus plays an important role in the binding of mRNA to the 43S pre-initiation complex of ribosomes. Human eIF4A2 interacts with the NS5B protein of Hepatitis C virus (HCV) and facilitates the genomic RNA synthesis of NS5B protein by unwinding the secondary structure of the HCV genome. It is ubiquitously expressed in most of normal tissues, but in variable amounts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: ATP dependent RNA helicase eIF4A 2; ATP-dependent RNA helicase eIF4A-2; eIF-4A-II; eIF4A-II; Eukaryotic initiation factor 4A-II; eukaryotic translation initiation factor 4A isoform 2; eukaryotic translation initiation factor 4A, isoform 2; N-terminally processed; protein synthesis initiation factor 4AII
Gene Aliases: 4833432N07Rik; BM-010; DDX2B; eIF-4A-II; Eif4; EIF4A; eIF4A-II; EIF4A2; EIF4F
UniProt ID: (Human) Q14240, (Mouse) P10630, (Rat) Q5RKI1
Entrez Gene ID: (Human) 1974, (Mouse) 13682, (Rat) 303831
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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