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Invitrogen
eIF3i Polyclonal Antibody
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Product Details
PA5-56301
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
Immunogen sequence: MGYQCFVSFF DLRDPSQIDN NEPYMKIPCN DSKITSAVWG PLGECIIAGH ESGELNQYSA KSGEVLVNVK EHSRQINDIQ LSRD
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 30%.
Target Information
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: eIF-3-beta; eIF3 p36; eIF3i; Eukaryotic translation initiation factor 3 subunit 2; Eukaryotic translation initiation factor 3 subunit I; eukaryotic translation initiation factor 3, subunit 1; eukaryotic translation initiation factor 3, subunit 2 (beta); eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD); eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa; eukaryotic translation initiation factor 3, subunit I; predicted protein of HQ2242; subuni; TGF-beta receptor binding protein; TGF-beta receptor-interacting protein 1; TGFbeta receptor-interacting protein 1; TRIP-1
Gene Aliases: 36kDa; D4Ertd632e; eIF3-beta; eIF3-p36; EIF3I; EIF3S2; PRO2242; TRIP-1; TRIP1
UniProt ID: (Human) Q13347, (Mouse) Q9QZD9, (Rat) B0BNA7
Entrez Gene ID: (Human) 8668, (Mouse) 54709, (Rat) 682390
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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