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Bioss
beta defensin 2 Polyclonal Antibody
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Product Details
BS-1296R
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
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Target Information
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: BD-2; beta defensin 2; beta defensin-2; Beta-defensin 2; Defensin beta 2; Defensin beta 4A; Defensin beta2; Defensin, beta 2; defensin, beta 4; defensin, beta 4A; Defensin-beta2; SAP1; Skin-antimicrobial peptide 1
Gene Aliases: BD-2; DEFB-2; DEFB102; DEFB2; DEFB4; DEFB4A; DEFB4B; HBD-2; SAP1
UniProt ID: (Human) O15263
Entrez Gene ID: (Human) 1673, (Rat) 641631
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