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  • Primary Antibodies ›
  • beta-Defensin 1 Antibodies

Invitrogen

beta-Defensin 1 Polyclonal Antibody

1 Reference
View all (10) beta-Defensin 1 antibodies

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Datasheet
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Questions & Answers

Cite beta-Defensin 1 Polyclonal Antibody

  • Antibody Testing Data (1)
beta-Defensin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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beta-Defensin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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beta-Defensin 1 Antibody (PA5-51286) in IHC (P)

Immunohistochemical analysis of beta-Defensin 1 in paraffin embedded Human ovarian cancer tissue using beta-Defensin 1 Polyclonal Antibody (Product # PA5-51286) at a 1:30 dilution. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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beta-Defensin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Details

PA5-51286

Applications
Tested Dilution
Publications

Immunohistochemistry (IHC)

-
View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:25-1:100
-
Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide of human DEFB1

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.9 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 40% glycerol

Contains

0.05% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2636733

Product Specific Information

The antibody detects endogenous levels of total DEFB1 protein.

Target Information

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: BD-1; beta defensin 1; Beta-defensin 1; beta-defensin-1; Defensin, beta 1

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Gene Aliases: BD1; DEFB-1; DEFB1; DEFB101; HBD1

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UniProt ID: (Human) P60022

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Entrez Gene ID: (Human) 1672

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Function(s)
protein binding CCR6 chemokine receptor binding
Process(es)
innate immune response in mucosa acute inflammatory response chemotaxis immune response G-protein coupled receptor signaling pathway response to bacterium antibacterial humoral response cAMP-mediated signaling response to testosterone calcium-mediated signaling using intracellular calcium source defense response to bacterium innate immune response defense response to Gram-negative bacterium defense response to Gram-positive bacterium positive regulation of sperm motility involved in capacitation
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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