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  • beta-Defensin 1 Antibodies

Bioss

beta Defensin 1 Polyclonal Antibody

View all (10) beta-Defensin 1 antibodies

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Datasheet
Protocols
Questions & Answers

Cite beta Defensin 1 Polyclonal Antibody

  • Antibody Testing Data (3)
beta Defensin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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beta Defensin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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beta Defensin 1 Antibody (BS-1163R) in IHC (P)

Paraformaldehyde-fixed, paraffin embedded rat kidney tissue; Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes; Blocking buffer (normal goat serum) at 37°C for 20min; Antibody incubation with Rabbit Anti-beta defensin 1 Polyclonal Antibody, Unconjugated (bs-1163R) at 1:200 overnight at 4°C, followed by a conjugated second... View More {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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beta Defensin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
beta Defensin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
beta Defensin 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
beta Defensin 1 Polyclonal Antibody

Product Details

BS-1163R

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200
-

Immunohistochemistry (Frozen) (IHC (F))

1:100-1:500
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

KLH conjugated synthetic peptide derived from rat Defensin Beta 1, amino acids 33-68.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

Contains

0.02% ProClin 300

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: BD-1; beta defensin 1; Beta-defensin 1; beta-defensin-1; Defensin, beta 1; rBD-1

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Gene Aliases: AW260221; BD-1; BD1; DEFB-1; DEFB1; DEFB101; HBD1

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UniProt ID: (Human) P60022, (Rat) O89117, (Mouse) P56386

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Entrez Gene ID: (Human) 1672, (Rat) 83687, (Mouse) 13214

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Function(s)
protein binding CCR6 chemokine receptor binding molecular_function
Process(es)
innate immune response in mucosa acute inflammatory response chemotaxis immune response G-protein coupled receptor signaling pathway response to bacterium antibacterial humoral response cAMP-mediated signaling response to testosterone calcium-mediated signaling using intracellular calcium source defense response to bacterium innate immune response defense response to Gram-negative bacterium defense response to Gram-positive bacterium positive regulation of sperm motility involved in capacitation defense response
It has to be done as per old AB suggested Products section.
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