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  • ZMPSTE24 Antibodies

Proteintech

ZMPSTE24 Polyclonal Antibody

View all (12) ZMPSTE24 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite ZMPSTE24 Polyclonal Antibody

  • Antibody Testing Data (3)
ZMPSTE24 Antibody in Immunocytochemistry (ICC/IF)
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ZMPSTE24 Antibody in Immunocytochemistry (ICC/IF)
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ZMPSTE24 Antibody (12847-1-AP) in ICC/IF

Immunofluorescent analysis of PC-3 cells using 12847-1-AP (ZMPSTE24 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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ZMPSTE24 Antibody in Immunocytochemistry (ICC/IF)
ZMPSTE24 Antibody in Western Blot (WB)
ZMPSTE24 Antibody in Immunoprecipitation (IP)
ZMPSTE24 Polyclonal Antibody

Product Details

12847-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

Immunocytochemistry (ICC/IF)

1:10-1:100
-

Immunoprecipitation (IP)

0.5-4.0 µg
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

ZMPSTE24 Fusion Protein Ag3949 (225-475 aa encoded by BC037283)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: KFTPLPEGK LKEEIEVMAK SIDFPLTKVY VVEGSKRSSH SNAYFYGFFK NKRIVLFDTL LEEYSVLNKD IQEDSGMEPR NEEEGNSEEI KAKVKNKKQG CKNEEVLAVL GHELGHWKLG HTVKNIIISQ MNSFLCFFLF AVLIGRKELF AAFGFYDSQP TLIGLLIIFQ FIFSPYNEVL SFCLTVLSRR FEFQADAFAK KLGKAKDLYS ALIKLNKDNL GFPVSDWLFS MWHYSHPPLL ERLQALKTMK QH (225-475 aa encoded by BC037283)

Target Information

This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CAAX prenyl protease 1 homolog; FACE-1; Farnesylated proteins-converting enzyme 1; FLJ14968; Prenyl protein-specific endoprotease 1; zinc metallopeptidase STE24 homolog; Zinc metalloproteinase Ste24 homolog

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Gene Aliases: FACE-1; FACE1; HGPS; PRO1; STE24; Ste24p; ZMPSTE24

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UniProt ID: (Human) O75844

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Entrez Gene ID: (Human) 10269

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Function(s)
metalloendopeptidase activity metalloexopeptidase activity metal ion binding
Process(es)
proteolysis nuclear envelope organization prenylated protein catabolic process CAAX-box protein processing
It has to be done as per old AB suggested Products section.
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