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  • XRCC1 Antibodies

OriGene

XRCC1 Monoclonal Antibody (OTI2E8), TrueMAB™

View all (42) XRCC1 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite XRCC1 Monoclonal Antibody (OTI2E8), TrueMAB™

  • Antibody Testing Data (2)
XRCC1 Antibody in Immunocytochemistry (ICC/IF)
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XRCC1 Antibody in Immunocytochemistry (ICC/IF)
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XRCC1 Antibody (TA500881) in ICC/IF

Anti-XRCC1 mouse monoclonal antibody (TA500881) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY XRCC1(RC204952). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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XRCC1 Antibody in Immunocytochemistry (ICC/IF)
XRCC1 Antibody in Western Blot (WB)
XRCC1 Monoclonal Antibody (OTI2E8), TrueMAB™

Product Details

TA500881

Applications
Tested Dilution
Publications

Western Blot (WB)

1:2,000
-

Immunocytochemistry (ICC/IF)

1:100
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI2E8

Immunogen

Full length human recombinant protein of human XRCC1 produced in HEK293T cell.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DNA repair protein XRCC1; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross-complementing protein 1

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Gene Aliases: RCC; XRCC1

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UniProt ID: (Human) P18887

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Entrez Gene ID: (Human) 7515

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Function(s)
damaged DNA binding DNA ligase activity protein binding enzyme binding
Process(es)
single strand break repair double-strand break repair via homologous recombination response to hypoxia transcription-coupled nucleotide-excision repair base-excision repair base-excision repair, DNA ligation nucleotide-excision repair, DNA gap filling response to organic substance response to drug
It has to be done as per old AB suggested Products section.
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