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Invitrogen
XRCC1 Polyclonal Antibody
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FIGURE: 1 / 11
XRCC1 Antibody (PA5-80237) in ICC/IF
Product Details
PA5-80237
Species Reactivity
Host/Isotype
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Type
Immunogen
Conjugate
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Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human 293T whole cell, human K562 whole cell, human Jurkat whole cell, rat brain tissue, rat liver tissue, mouse brain tissue, mouse liver tissue. IHC: rat kidney tissue, human placenta tissue, human colon cancer tissue, human mammary cancer tissue IHC-F: rat intestine tissue, human placenta tissue, mouse intestine tissue. ICC/IF: NIH3T3 cell. Flow: THP-1 cell.
Target Information
XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: DNA repair protein XRCC1; X-ray repair complementing defective repair in Chinese hamster cells 1; x-ray repair cross-complementing group 1 protein; X-ray repair cross-complementing protein 1
Gene Aliases: RCC; Xrcc-1; XRCC1
UniProt ID: (Human) P18887, (Rat) Q9ESZ0, (Mouse) Q60596
Entrez Gene ID: (Human) 7515, (Rat) 84495, (Mouse) 22594
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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