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  • Primary Antibodies ›
  • XRCC1 Antibodies

Bethyl Laboratories

XRCC1 Polyclonal Antibody

View all (42) XRCC1 antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite XRCC1 Polyclonal Antibody

  • Antibody Testing Data (1)
XRCC1 Antibody in Western Blot (WB)
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XRCC1 Antibody in Western Blot (WB)
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XRCC1 Antibody (A300-065A) in WB

Detection of human XRCC1 by western blot. Sample: Whole cell extract (50 µg) from mock treated or siRNA treated HeLa cells. Antibody: Affinity purified rabbit anti-XRCC1 Product # A300-065A) used for WB at 1 µg/mL. Detection: Chemiluminescence. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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XRCC1 Antibody in Western Blot (WB)
XRCC1 Polyclonal Antibody

Product Details

A300-065A

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:10,000
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Region between residue 600 and the C-terminus (residue 633) of Human X-ray Repair Cross Complementing protein 1.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

phosphate/tris citrate, pH 7-8

Contains

0.09% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

Target Information

XRCC1 (X-ray cross complementing factor-1) is involved in DNA base excision repair. XRCC1 is a 70 kDa protein that has been shown to be physically associated with other DNA repair enzymes, including poly (ADP-ribose) polymerase (PARP), DNA Ligase III and DNA polymerase beta. XRCC1 contains a BRCT domain (for BRCA1 carboxyl terminus) which was originally found in the tumor suppressor protein BRCA1. Recently, the BRCT domain has been shown to mediate the protein-protein interaction of XRCC1 and DNA ligase III-alpha.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DNA repair protein XRCC1; X-ray repair complementing defective repair in Chinese hamster cells 1; X-ray repair cross-complementing protein 1

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Gene Aliases: RCC; XRCC1

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UniProt ID: (Human) P18887

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Entrez Gene ID: (Human) 7515

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Function(s)
damaged DNA binding DNA ligase activity protein binding enzyme binding
Process(es)
single strand break repair double-strand break repair via homologous recombination response to hypoxia transcription-coupled nucleotide-excision repair base-excision repair base-excision repair, DNA ligation nucleotide-excision repair, DNA gap filling response to organic substance response to drug
It has to be done as per old AB suggested Products section.
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