Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
Willin Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
21039-1-AP
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Although willin is found in the cytoplasm and membrane, it localizes to the nuclei of almost all tumors. This antibody was raised against the C-terminal region of human FRMD6 protein and is expected to recognize the endogenous FRMD6.
Immunogen sequence: LDMDQLEKR SRASGSSAGS MKHKRLSRHS TASHSSSHTS GIEADTKPRD TGPEDSYSSS AIHRKLKTCS SMTSHGSSHT SGVESGGKDR LEEDLQDDEI EMLVDDPRDL EQMNEESLEV SPDMCIYITE DMLMSRKLNG HSGLIVKEIG SSTSSSSETV VKLRGQSTDS LPQTICRKPK TSTDRHSLSL DDIRLYQKDF LRIAGLCQDT AQSYTFGCGH ELDEEGLYCN SCLAQQCINI QDAFPVKRTS KYFSLDLTHD EVPEFVV (359-622 aa encoded by BC029870 )
Target Information
The protein encoded by this gene interacts with signaling pathways to coordinately regulate cell growth, cell proliferation, apoptosis, autophagy, and cell migration. This tumor suppressor also enhances retinoblastoma 1 gene expression in cancer cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: 4.1 ezrin radixin moesin (FERM)-containing protein; expanded homolog; FERM domain-containing protein 163SCII; FERM domain-containing protein 6; FERM-domain-containing protein 163SCII; MGC17921; Willin
Gene Aliases: 2610019M19Rik; 4930488L10Rik; AW212977; c14_5320; C14orf31; EX1; FRMD6; Willin
UniProt ID: (Human) Q96NE9, (Mouse) Q8C0V9
Entrez Gene ID: (Human) 122786, (Rat) 257646, (Mouse) 319710
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support