NeoBiotechnologies

Villin (GI-Mucosal and Urogenital Brush Border Marker) Recombinant Rabbit Monoclonal Antibody (VIL1/2310R)

Name: Villin (GI-Mucosal and Urogenital Brush Border Marker) Recombinant Rabbit Monoclonal Antibody (VIL1\/2310R)
Brand: NeoBiotechnologies
SKU: 7429-RBM4-P0

View all (53) Villin antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (4)

Villin (GI-Mucosal and Urogenital Brush Border Marker) Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 4

Villin (GI-Mucosal and Urogenital Brush Border Marker) Antibody (7429-RBM4-P0) in IHC (P)

Formalin-fixed, paraffin-embedded human Small Intestine stained with Villin Rabbit Recombinant Monoclonal Antibody (VIL1/2310R).

Villin (GI-Mucosal and Urogenital Brush Border Marker) Antibody in Western Blot (WB)

Villin (GI-Mucosal and Urogenital Brush Border Marker) Antibody in SDS-PAGE (SDS-PAGE)

Product Image Gallery

Immunogen image

Immunogen Image Villin (GI-Mucosal and Urogenital Brush Border Marker) Recombinant Rabbit Monoclonal Antibody (VIL1/2310R)

Product Details

7429-RBM4-P0

Applications

Tested Dilution

Publications

Western Blot (WB)

1-2 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

Immunohistochemistry (PFA fixed) (IHC (PFA))

1-2 µg/mL

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG, kappa

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

VIL1/2310R

Immunogen

A recombinant fragment (around aa179-311) of human Villin protein.

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4°C, do not freeze

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Villin is part of cytoskeleton associated with the microvillar actin core bundle of gastrointestinal and renal brush border. It can interact with actin in a Ca2+ and phosphoinositide-regulated manner. Villin is a very specific marker for adenocarcinomas of the gastrointestinal tract and the pancreas. It is also expressed in some Merkel cell tumor and adenocarcinoma of the lung, prostate, ovarian and kidney.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: OTTHUMP00000207159; Villin-1

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Gene Aliases: D2S1471; VIL; VIL1

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UniProt ID: (Human) P09327

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Entrez Gene ID: (Human) 7429

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Function(s)

calcium ion binding protein binding phosphatidylinositol-4,5-bisphosphate binding lysophosphatidic acid binding identical protein binding protein homodimerization activity cysteine-type endopeptidase inhibitor activity involved in apoptotic process actin filament binding

Process(es)

intestinal D-glucose absorption protein complex assembly apoptotic process epidermal growth factor receptor signaling pathway regulation of cell shape response to bacterium positive regulation of epithelial cell migration actin filament polymerization actin filament depolymerization positive regulation of cell migration positive regulation of actin filament depolymerization epithelial cell differentiation positive regulation of actin filament bundle assembly regulation of microvillus length cellular response to hepatocyte growth factor stimulus positive regulation of multicellular organism growth negative regulation of cysteine-type endopeptidase activity involved in apoptotic process actin nucleation actin filament severing barbed-end actin filament capping regulation of actin nucleation actin filament capping cytoplasmic actin-based contraction involved in cell motility regulation of wound healing cellular response to epidermal growth factor stimulus positive regulation of establishment of protein localization to plasma membrane terminal web assembly regulation of lamellipodium morphogenesis positive regulation of lamellipodium morphogenesis

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Villin (GI-Mucosal and Urogenital Brush Border Marker) Recombinant Rabbit Monoclonal Antibody (VIL1/2310R)

Villin (GI-Mucosal and Urogenital Brush Border Marker) Antibody (7429-RBM4-P0) in IHC (P)

Product Details

7429-RBM4-P0

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (PFA fixed) (IHC (PFA))

Species Reactivity

Host/Isotype

Expression System

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Target Information

References (0)

Bioinformatics

Performance Guarantee

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