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Invitrogen
Versican Monoclonal Antibody (N351/23)
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FIGURE: 1 / 4
Versican Antibody (MA5-27638) in ICC/IF
Product Details
MA5-27638
Species Reactivity
Published species
Host/Isotype
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Type
Clone
Immunogen
Conjugate
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Product Specific Information
1 µg/mL of MA5-27638 was sufficient for detection of Versican in 20 µg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.|Detects >350kDa.
This antibody was formerly sold as clone S351-23
Target Information
Versican is a member of the family of large aggregating proteoglycans (also including aggrecan, brevican, and neurocan). The protein shows wide tissue distribution which includes fibrous, articular, and elastic cartilages, as well as nervous, epidermal, arterial, and loose connective tissues. Versican V1 has been shown to enhance cell proliferation, and also induce cell transformation and protect cells from apoptosis. This was demonstrated through its ability to downregulate the expression of proapoptotic Bad. Versican's existence as a extracellular matrix protein in human airways has also lead to the discovery of an inflammatory role in asthmatics.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Chondroitin sulfate proteoglycan 2; chondroitin sulfate proteoglycan 2 (versican); Chondroitin sulfate proteoglycan core protein 2; GHAP; Glial hyaluronate-binding protein; heart defect; Large fibroblast proteoglycan; PG-M; PG-M core protein; PGM; V1 Neo; Versican core protein; Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M); versican proteoglycan; Versican V0; WGN 1
Gene Aliases: 5430420N07Rik; 9430051N09; CSPG2; DPEAAE; ERVR; GHAP; hdf; NG2; PG-M; PG-M(V0); PG-M(V1); VCAN; WGN; WGN1
UniProt ID: (Human) P13611, (Rat) Q9ERB4
Entrez Gene ID: (Human) 1462, (Mouse) 13003, (Rat) 114122
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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