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  • VMAT2 Antibodies

Invitrogen

VMAT2 Monoclonal Antibody (OTI10C11)

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite VMAT2 Monoclonal Antibody (OTI10C11)

  • Antibody Testing Data (4)
VMAT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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VMAT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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VMAT2 Antibody (MA5-24930) in IHC (P)

Immunohistochemistry was performed on paraffin-embedded adenocarcinoma of breast tissue. To expose target proteins, 10mM citric buffer, pH6.0, 100°C for 10min was used. Following antigen retrieval, tissues were probed with a SLC18A2 monoclonal antibody (Product # MA5-24930) at a dilution of 1:50. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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VMAT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
VMAT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
VMAT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
VMAT2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
VMAT2 Monoclonal Antibody (OTI10C11)

Product Details

MA5-24930

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

OTI10C11

Immunogen

Full-length protein expressed in 293T cell transfected with human SLC18A2 expression vector
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.0 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2725664

Target Information

VMAT2 is involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. It is a requisite for vesicular amine storage prior to secretion via exocytosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: MGC120477; MGC120478; MGC26538; monoamine neurotransmitter transporter; monoamine transporter; solute carrier family 18 (vesicular monoamine transporter), member 2; solute carrier family 18 (vesicular monoamine), member 2; Solute carrier family 18 member 2; Synaptic vesicular amine transporter; VAT2; vesicle monoamine transporter type 2; vesicle monoamine/H+ antiporter; Vesicular amine transporter 2; Vesicular monoamine transporter 2

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Gene Aliases: SLC18A2; SVAT; SVMT; VAT2; VMAT2

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UniProt ID: (Human) Q05940

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Entrez Gene ID: (Human) 6571

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Function(s)
amine transmembrane transporter activity drug binding monoamine transmembrane transporter activity serotonin transmembrane transporter activity enzyme binding heat shock protein binding
Process(es)
response to amphetamine serotonin transport chemical synaptic transmission neurotransmitter secretion aging locomotory behavior response to herbicide post-embryonic development response to zinc ion aminergic neurotransmitter loading into synaptic vesicle monoamine transport dopamine transport insulin secretion endocytic recycling cellular response to drug sequestering of neurotransmitter response to cocaine glucose homeostasis response to starvation response to corticosterone negative regulation of neurotransmitter transport transmembrane transport cellular response to ammonium ion neurotransmitter loading into synaptic vesicle negative regulation of reactive oxygen species biosynthetic process
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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