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  • VASH1 Antibodies

Invitrogen

VASH1 Polyclonal Antibody

View all (10) VASH1 antibodies

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Cite VASH1 Polyclonal Antibody

  • Antibody Testing Data (1)
VASH1 Antibody in Western Blot (WB)
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VASH1 Antibody in Western Blot (WB)
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VASH1 Antibody (PA5-96518) in WB

Western blot analysis of VASH1 in extracts of various cell lines. Samples were incubated with VASH1 Polyclonal antibody (Product # PA5-96518) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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VASH1 Antibody in Western Blot (WB)
VASH1 Polyclonal Antibody

Product Details

PA5-96518

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-365 of human VASH1 (NP_0557241)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.56 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2808320

Product Specific Information

Immunogen sequence: MPGGKKVAGG GSSGATPTSA AATAPSGVRR LETSEGTSAQ RDEEPEEEGE EDLRDGGVPF FVNRGGLPVD EATWERMWKH VAKIHPDGEK VAQRIRGATD LPKIPIPSVP TFQPSTPVPE RLEAVQRYIR ELQYNHTGTQ FFEIKKSRPL TGLMDLAKEM TKEALPIKCL EAVILGIYLT NSMPTLERFP ISFKTYFSGN YFRHIVLGVN FAGRYGALGM SRREDLMYKP PAFRTLSELV LDFEAAYGRC WHVLKKVKLG QSVSHDPHSV EQIEWKHSVL DVERLGRDDF RKELERHARD MRLKIGKGTG PPSPTKDRKK DVSSPQRAQS SPHRRNSRSE RRPSGDKKTS EPKAMPDLNG YQIRV; Positive Samples: THP-1, Mouse brain, Mouse stomach

Target Information

VASH1 is a protein that possesses actin binding activity and metallocarboxypeptidase activity. It is involved in several processes including negative regulation of angiogenesis, negative regulation of blood vessel endothelial cell migration, and proteolysis. VASH1 acts upstream of or within processes such as negative regulation of endothelial cell migration, negative regulation of endothelial cell proliferation, and negative regulation of lymphangiogenesis. It is located in the apical part of the cell, endoplasmic reticulum, and extracellular space. VASH1 is implicated in liver cirrhosis and portal hypertension, and is a biomarker of liver cirrhosis. Diseases associated with VASH1 include Portal Hypertension and Myasthenic Syndrome, Congenital, 14.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: TTCP 1; Tubulin carboxypeptidase 1; Tubulinyl-Tyr carboxypeptidase 1; Tyrosine carboxypeptidase 1; Vasohibin-1

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Gene Aliases: AI834978; D930046M13Rik; G630009D10Rik; KIAA1036; VASH; VASH1

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UniProt ID: (Human) Q7L8A9, (Mouse) Q8C1W1

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Entrez Gene ID: (Human) 22846, (Mouse) 238328

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Function(s)
protein binding molecular_function
Process(es)
angiogenesis negative regulation of endothelial cell proliferation cell cycle arrest response to wounding negative regulation of endothelial cell migration negative regulation of angiogenesis negative regulation of blood vessel endothelial cell migration negative regulation of lymphangiogenesis regulation of cellular senescence cell cycle positive regulation of gene expression regulation of angiogenesis
It has to be done as per old AB suggested Products section.
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