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  • Primary Antibodies ›
  • Uteroglobin Antibodies

Proteintech

Uteroglobin Polyclonal Antibody

16 References
View all (24) Uteroglobin antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Uteroglobin Polyclonal Antibody

  • Antibody Testing Data (4)
Uteroglobin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Uteroglobin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Uteroglobin Antibody (10490-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded mouse lung tissue slide using 10490-1-AP ( Uteroglobin Antibody) at dilution of 1:200 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Uteroglobin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Uteroglobin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Uteroglobin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Uteroglobin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Uteroglobin Polyclonal Antibody

Product Details

10490-1-AP

Applications
Tested Dilution
Publications

Western Blot (WB)

-
View 2 publications 2 publications

Immunohistochemistry (IHC)

-
View 7 publications 7 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500
-

Immunocytochemistry (ICC/IF)

-
View 4 publications 4 publications

Flow Cytometry (Flow)

Assay-dependent
View 2 publications 2 publications

Immunoprecipitation (IP)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse

Published species

Bovine, Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Uteroglobin Fusion Protein Ag0758 (1-91 aa encoded by BC004481)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MKLAVTLTL VTLALCCSSA SAEICPSFQR VIETLLMDTP SSYEAAMELF SPDQDMREAG AQLKKLVDTL PQKPRESIIK LMEKIAQSSL CN (1-91 aa encoded by BC004481)

Target Information

Uteroglobin, which is a member of the Secretoglobin superfamily and is also known as Clara cell phospholipid-binding protein, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. The small, non-glycosylated protein named for its high levels of expression in pre-implantation embryos, where it exhibits growth stimulatory effects, is produced and secreted by the non-ciliated, non-mucous Clara cells predominant in the epithelial surfaces of pulmonary airways, as well as other non-ciliated epithelia. Members of the Secretoglobin superfamily demonstrate a high level of structural conservation and are characterized as small, secretory homo- or heterodimers. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Blastokinin; CC10; CCPBP; clara cell 17 kDa protein; clara cell phospholipid-binding protein; clara cell secretory protein; clara cells 10 kDa secretory protein; Club cell 17 kDa protein; Club cell phospholipid-binding protein; Club cells 10 kDa secretory protein; PCB-binding protein; Secretoglobin family 1A member 1; secretoglobin, family 1A, member 1 (uteroglobin); UP-1; Urinary protein 1; urine protein 1; Uteroglobin

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Gene Aliases: CC10; CC16; CCPBP; CCSP; PCB-BP; SCGB1A1; UG; UGB; UP-1; UP1; Utg

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UniProt ID: (Human) P11684, (Mouse) Q06318

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Entrez Gene ID: (Human) 7356, (Mouse) 22287

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Function(s)
protein binding phospholipase A2 inhibitor activity polychlorinated biphenyl binding
Process(es)
negative regulation of transcription from RNA polymerase II promoter signal transduction negative regulation of interferon-gamma production negative regulation of interleukin-13 production negative regulation of interleukin-4 production negative regulation of interleukin-5 production response to cytokine negative regulation of T cell proliferation regulation of mRNA stability regulation of inflammatory response female pregnancy embryo implantation response to xenobiotic stimulus response to ozone response to lipopolysaccharide response to silicon dioxide response to drug negative regulation of catalytic activity response to glucocorticoid response to fibroblast growth factor
It has to be done as per old AB suggested Products section.
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