Huabio

Tyk2 Polyclonal Antibody

Name: Tyk2 Polyclonal Antibody
Brand: Huabio
SKU: ER1803-05

View all (23) TYK2 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (6)

Tyk2 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 6

Tyk2 Antibody (ER1803-05) in ICC/IF

ICC staining of Tyk2 in MCF-7 cells (green). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 10% negative goat serum for 15 minutes at room temperature. Cells were probed with the primary antibody (ER1803-05, 1:50) for 1 hour at room temperature, washed with PBS. Alexa Fluor®488 conjugate-Goat anti-Rabbit IgG was used as the secondary antibody at 1:1,000 dilution. The nuclear counter stain is DAPI (blue).

Tyk2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Immunogen image

Immunogen Image Tyk2 Polyclonal Antibody

Product Details

ER1803-05

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

Immunocytochemistry (ICC/IF)

1:50-1:200

Flow Cytometry (Flow)

1:50-1:100

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein within human TYK2 aa 390-620.

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 0.2% BSA, 50% glycerol

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Tyrosine Kinase 2 (TYK2) a member of the JAK kinase family, plays both structural and catalytic roles in type I interferon (IFN) signaling. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 4833430L21Rik; AW540162; BRE1; BRE1A; C79397; hBRE1; mKIAA4116; Non-receptor tyrosine-protein kinase TYK2

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Gene Aliases: IMD35; JTK1; TYK2

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UniProt ID: (Human) P29597

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Entrez Gene ID: (Human) 7297, (Rat) 100361294

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Function(s)

protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity growth hormone receptor binding protein binding ATP binding type 1 angiotensin receptor binding hormone receptor binding

Process(es)

transmembrane receptor protein tyrosine kinase signaling pathway cell migration cell differentiation intracellular signal transduction peptidyl-tyrosine autophosphorylation regulation of cell proliferation innate immune response protein phosphorylation type I interferon signaling pathway regulation of type I interferon-mediated signaling pathway

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Tyk2 Polyclonal Antibody

Tyk2 Antibody (ER1803-05) in ICC/IF

Product Details

ER1803-05

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Target Information

References (0)

Bioinformatics

Performance Guarantee

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