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  • Trypsin 2 Antibodies

Invitrogen

Trypsin 2 Recombinant Rabbit Monoclonal Antibody (12H7)

View all (16) Trypsin 2 antibodies

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Datasheet
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Datasheet
Protocols
Questions & Answers

Cite Trypsin 2 Recombinant Rabbit Monoclonal Antibody (12H7)

  • Antibody Testing Data (1)
Trypsin 2 Antibody in Immunocytochemistry (ICC/IF)
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Trypsin 2 Antibody in Immunocytochemistry (ICC/IF)
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Trypsin 2 Antibody (MA5-50035) in ICC/IF

Immunocytochemistry analysis of Jurkat cell with Trypsin 2 monoclonal antibody (Product # MA5-50035) at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 562-congugated AffiniPure Goat Anti-Rabbit IgG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Trypsin 2 Antibody in Immunocytochemistry (ICC/IF)

Product Details

MA5-50035

Applications
Tested Dilution
Publications

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

Assay-dependent
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

12H7

Immunogen

A synthesized peptide derived from human PRSS2

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.33 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_3092680

Target Information

This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Anionic trypsinogen; EC 3.4.21; EC 3.4.21.4; MGC111183; MGC120174; MGC120175; protease serine 2 preproprotein; protease, serine, 2 (trypsin 2); Serine protease 2; Trypsin II; trypsin Trypsin II; Trypsin-2; trypsinogen 2

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Gene Aliases: PRSS2; TRY2; TRY8; TRYP2

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UniProt ID: (Human) P07478

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Entrez Gene ID: (Human) 5645

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Function(s)
serine-type endopeptidase activity calcium ion binding protein binding serine-type peptidase activity
Process(es)
proteolysis digestion extracellular matrix disassembly positive regulation of cell growth collagen catabolic process positive regulation of cell adhesion
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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