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  • TrkA/TrkB/TrkC Antibodies

Invitrogen

TrkA/TrkB/TrkC Recombinant Rabbit Monoclonal Antibody (RM423)

View all (12) TrkA/TrkB/TrkC antibodies

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Datasheet
Protocols
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Datasheet
Protocols
Questions & Answers

Cite TrkA/TrkB/TrkC Recombinant Rabbit Monoclonal Antibody (RM423)

  • Antibody Testing Data (2)
TrkA/TrkB/TrkC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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TrkA/TrkB/TrkC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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TrkA/TrkB/TrkC Antibody (MA5-36218) in IHC (P)

Immunohistochemistry analysis of formalin fixed and paraffin embedded human brain tissue usingTrkA/TrkB/TrkC Recombinant Monoclonal antibody (Product # MA5-36218) at a dilution of 1:100. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TrkA/TrkB/TrkC Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TrkA/TrkB/TrkC Antibody in Western Blot (WB)
TrkA/TrkB/TrkC Recombinant Rabbit Monoclonal Antibody (RM423)

Product Details

MA5-36218

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:200
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

RM423

Immunogen

A peptide corresponding to the C-terminus of human TRK
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.08 mg/mL

Purification

Protein A

Storage buffer

PBS with 50% glycerol, 1% BSA

Contains

0.09% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2884052

Product Specific Information

MA5-36218 reacts to human TRK. This antibody may also react to mouse or rat TRK, as predicted by immunogen homology.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: BDNF-tropomyosine receptor kinase B; BDNF/NT-3 growth factors receptor; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp140trk; GP145-TrkB; GP145-TrkC; High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; Neurotrophic tyrosine kinase receptor type 2; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 1; neurotrophic tyrosine kinase, receptor, type 2; neurotrophic tyrosine kinase, receptor, type 3; NT-3 growth factor receptor; Oncogene TRK; p140-TrkA; Trk-A; Trk-B; Trk-C; TRK1-transforming tyrosine kinase protein; TrkB tyrosine kinase; TrkC tyrosine kinase; Tropomyosin-related kinase A; Tropomyosin-related kinase B; Tyrosine kinase receptor; Tyrosine kinase receptor A; tyrosine kinase receptor B; tyrosine kinase receptor C

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Gene Aliases: gp145(trkC); GP145-TrkB; GP145-TrkC; MTC; NTRK1; NTRK2; NTRK3; p140-TrkA; TRK; Trk-A; trk-B; TRK1; TRKA; TRKB; TRKC

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UniProt ID: (Human) P04629, (Human) Q16620, (Human) Q16288

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Entrez Gene ID: (Human) 4914, (Human) 4915, (Human) 4916

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Function(s)
transmembrane receptor protein tyrosine kinase activity GPI-linked ephrin receptor activity neurotrophin p75 receptor binding protein binding ATP binding nerve growth factor receptor activity kinase binding protein homodimerization activity neurotrophin binding nerve growth factor binding receptor tyrosine kinase binding brain-derived neurotrophic factor binding brain-derived neurotrophic factor-activated receptor activity p53 binding neurotrophin receptor activity
Process(es)
vasculogenesis neuron migration positive regulation of protein phosphorylation inflammatory response neuromuscular junction development aging learning long-term memory circadian rhythm feeding behavior positive regulation of cell proliferation response to light stimulus positive regulation of gene expression positive regulation of neuron projection development response to auditory stimulus glutamate secretion positive regulation of phosphatidylinositol 3-kinase signaling peptidyl-tyrosine phosphorylation central nervous system neuron development cerebral cortex development neuron differentiation brain-derived neurotrophic factor receptor signaling pathway positive regulation of peptidyl-serine phosphorylation calcium-mediated signaling using intracellular calcium source neurotrophin signaling pathway mechanoreceptor differentiation regulation of GTPase activity positive regulation of MAPK cascade negative regulation of neuron apoptotic process retinal rod cell development protein autophosphorylation regulation of neurotransmitter secretion oligodendrocyte differentiation peripheral nervous system neuron development positive regulation of axonogenesis regulation of dendrite development regulation of protein kinase B signaling positive regulation of synapse assembly positive regulation of synaptic transmission, glutamatergic retina development in camera-type eye long-term synaptic potentiation cellular response to amino acid stimulus cellular response to tumor necrosis factor cellular response to brain-derived neurotrophic factor stimulus negative regulation of anoikis activation of MAPK activity negative regulation of protein phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway heart development modulation by virus of host transcription positive regulation of cell migration activation of protein kinase B activity positive regulation of apoptotic process response to ethanol ephrin receptor signaling pathway neuron fate specification response to axon injury positive regulation of axon extension involved in regeneration negative regulation of astrocyte differentiation positive regulation of positive chemotaxis response to corticosterone negative regulation of cell death lens fiber cell differentiation cellular response to retinoic acid cochlea development activation of GTPase activity positive regulation of actin cytoskeleton reorganization activation of MAPKK activity protein phosphorylation microtubule-based movement axon guidance learning or memory negative regulation of cell proliferation response to radiation programmed cell death involved in cell development response to activity olfactory nerve development B cell differentiation response to nutrient levels nerve growth factor signaling pathway response to drug positive regulation of programmed cell death positive regulation of GTPase activity positive regulation of Ras protein signal transduction neurotrophin TRK receptor signaling pathway phosphatidylinositol-mediated signaling sympathetic nervous system development detection of temperature stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of pain positive regulation of NF-kappaB transcription factor activity response to hydrostatic pressure response to electrical stimulus Sertoli cell development axonogenesis involved in innervation behavioral response to formalin induced pain positive regulation of ERK1 and ERK2 cascade cellular response to nicotine cellular response to nerve growth factor stimulus
It has to be done as per old AB suggested Products section.
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