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Invitrogen
Treslin Polyclonal Antibody
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Product Details
PA5-38053
Species Reactivity
Host/Isotype
Class
Type
Immunogen
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
RRID
Product Specific Information
A recommended positive control is human small intestine tissue lysate.
At least two isoforms of TICRR are known to exist.
Target Information
Regulator of DNA replication and S/M and G2/M checkpoints. Regulates the triggering of DNA replication initiation via its interaction with TOPBP1 by participating in CDK2-mediated loading of CDC45L onto replication origins. Required for the transition from pre-replication complex (pre-RC) to pre-initiation complex (pre-IC). Required to prevent mitotic entry after treatment with ionizing radiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: TOPBP1-interacting checkpoint and replication regulator; topBP1-interacting replication-stimulating protein; TopBP1-interacting, replication-stimulating protein; Treslin
Gene Aliases: C15orf42; SLD3; TICRR; Treslin
UniProt ID: (Human) Q7Z2Z1
Entrez Gene ID: (Human) 90381
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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