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Transferrin (Early Marker of Oligodendrocytes) Monoclonal Antibody (TF/4796)

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Cite Transferrin (Early Marker of Oligodendrocytes) Monoclonal Antibody (TF/4796)

  • Antibody Testing Data (1)
Transferrin (Early Marker of Oligodendrocytes) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Transferrin (Early Marker of Oligodendrocytes) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Transferrin (Early Marker of Oligodendrocytes) Antibody (7018-MSM6-P1) in IHC (P)

Formalin-fixed, paraffin-embedded human liver stained with Transferrin Mouse Monoclonal Antibody (TF/4796). HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Transferrin (Early Marker of Oligodendrocytes) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Transferrin (Early Marker of Oligodendrocytes) Monoclonal Antibody (TF/4796)

Product Details

7018-MSM6-P1

Applications
Tested Dilution
Publications

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL
-

ELISA (ELISA)

2-4 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2, kappa

Class

Monoclonal

Type

Antibody

Clone

TF/4796

Immunogen

Recombinant fragment (around aa 311-445) of human TF protein.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4°C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive Control:Human liver or hepatocellular carcinoma.

Cellular Location: Secreted

Target Information

Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Beta-1 metal-binding globulin; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; Serotransferrin; Siderophilin; transferin; Transferrin

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Gene Aliases: HEL-S-71p; PRO1400; PRO1557; PRO2086; TF; TFQTL1

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UniProt ID: (Human) P02787

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Entrez Gene ID: (Human) 7018

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Function(s)
protein binding ferrous iron binding ferric iron binding ferric iron transmembrane transporter activity transferrin receptor binding
Process(es)
retina homeostasis platelet degranulation cellular iron ion homeostasis regulation of protein stability transferrin transport positive regulation of receptor-mediated endocytosis iron ion homeostasis cellular response to iron ion ferrous iron import into cell
It has to be done as per old AB suggested Products section.
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