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  • Transferrin Antibodies

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Transferrin Polyclonal Antibody

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Datasheet
Protocols
Questions & Answers

Cite Transferrin Polyclonal Antibody

  • Antibody Testing Data (3)
Transferrin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Transferrin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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Transferrin Antibody (BS-2052R) in IHC (P)

Formalin-fixed and paraffin embedded rat liver tissue labeled with Anti-Transferrin Polyclonal Antibody, Unconjugated (bs-2052R) at 1:200 followed by conjugation to the secondary antibody and DAB staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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Transferrin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
Transferrin Antibody in Western Blot (WB)
Transferrin Antibody in Western Blot (WB)
Transferrin Polyclonal Antibody

Product Details

BS-2052R

Applications
Tested Dilution
Publications

Western Blot (WB)

1:300-1:5,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:400
-

ELISA (ELISA)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Goat, Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Full length native Transferrin protein purified from human plasma.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

TBS, pH 7.4, with 50% glycerol, 1% BSA

Contains

0.03% ProClin 300

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Beta-1 metal-binding globulin; DKFZp781D0156; epididymis secretory sperm binding protein Li 71p; hypotransferrinemia with hemochromatosis; Liver regeneration-related protein LRRG03; Serotransferrin; Siderophilin; transferin; Transferrin

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Gene Aliases: AI266983; Cd176; HEL-S-71p; HP; hpx; PRO1400; PRO1557; PRO2086; TF; Tfn; TFQTL1; Trf

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UniProt ID: (Human) P02787, (Rat) P12346, (Mouse) Q921I1

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Entrez Gene ID: (Human) 7018, (Rat) 24825, (Mouse) 22041

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Function(s)
protein binding ferrous iron binding ferric iron binding ferric iron transmembrane transporter activity transferrin receptor binding GTP binding metal ion binding
Process(es)
transport ion transport iron ion transport cellular iron ion homeostasis actin filament organization activation of JUN kinase activity ferric iron transport osteoclast differentiation positive regulation of myelination iron ion transmembrane transport positive regulation of phosphorylation positive regulation of bone resorption positive regulation of transcription, DNA-templated iron ion homeostasis SMAD protein signal transduction ERK1 and ERK2 cascade positive regulation of oligodendrocyte progenitor proliferation positive regulation of cell motility response to hypoxia retina homeostasis apoptotic process acute-phase response small GTPase mediated signal transduction response to lead ion response to organic cyclic compound cellular response to cAMP cellular response to follicle-stimulating hormone stimulus platelet degranulation regulation of protein stability transferrin transport positive regulation of receptor-mediated endocytosis cellular response to iron ion ferrous iron import into cell
It has to be done as per old AB suggested Products section.
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