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  • Transferrin Antibodies

Rockland

Transferrin Polyclonal Antibody

View all (97) Transferrin antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite Transferrin Polyclonal Antibody

Transferrin Polyclonal Antibody

Product Details

600-401-255

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-

ELISA (ELISA)

Assay-dependent
-

Immunoprecipitation (IP)

Assay-dependent
-
Product Specifications

Species Reactivity

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Mouse Transferrin
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

0.02M potassium phosphate, pH 7.2, with 0.15M NaCl

Contains

0.01% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. Analysis by SDS-PAGE was used to determine that this preparation is substantially free of aggregates and shows a banding pattern consistent with purified Rabbit IgG.

Target Information

Transferrins (Tf) are an approximately 80kDa blood plasma glycoprotein synthesized by the liver. They are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Transferrin is the primary blood iron transport protein and under normal conditions; approximately one-third of total blood transferrin contains bound iron. Measurement of blood transferrin levels can be used as an indicator for blood iron-carrying capacity and abnormalities of iron metabolism such as anaemia, iron overload and haemochromatosis.Serum transferrin may also have a further role in stimulating cell proliferation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Beta-1 metal-binding globulin; DKFZp781D0156; hypotransferrinemia with hemochromatosis; Serotransferrin; Siderophilin; transferin; Transferrin

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Gene Aliases: AI266983; Cd176; HP; hpx; Tf; Tfn; Trf

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UniProt ID: (Mouse) Q921I1

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Entrez Gene ID: (Mouse) 22041

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Function(s)
protein binding ferric iron binding ferric iron transmembrane transporter activity metal ion binding
Process(es)
transport ion transport iron ion transport cellular iron ion homeostasis actin filament organization activation of JUN kinase activity ferric iron transport osteoclast differentiation positive regulation of myelination iron ion transmembrane transport positive regulation of phosphorylation positive regulation of bone resorption positive regulation of transcription, DNA-templated iron ion homeostasis SMAD protein signal transduction ERK1 and ERK2 cascade positive regulation of oligodendrocyte progenitor proliferation positive regulation of cell motility
It has to be done as per old AB suggested Products section.
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