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Invitrogen
Thyroglobulin Recombinant Rabbit Monoclonal Antibody (3I10H1)
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Thyroglobulin Antibody (MA5-42809) in IHC (P)
Product Details
MA5-42809
Species Reactivity
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Product Specific Information
The target is usually found in the following locations: Secreted.
Immunogen sequence: STLSFYQRRR FSPDDSAGAS ALLRSGPYMP QCDAFGSWEP VQCHAGTGHC WCVDEKGGFI PGSLTARSLQ IPQCPTTCEK SRTSGLLSSW KQARSQENPS P
Target Information
The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Colloid; congenital goiter; Tg; Thyroglobulin
Gene Aliases: AITD3; cog; TG; TGN
UniProt ID: (Human) P01266, (Mouse) O08710
Entrez Gene ID: (Human) 7038, (Mouse) 21819, (Rat) 24826
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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