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Invitrogen

TROY Recombinant Rabbit Monoclonal Antibody (1R8Y5)

View all (21) TROY antibodies

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Datasheet
Protocols
Questions & Answers

Cite TROY Recombinant Rabbit Monoclonal Antibody (1R8Y5)

  • Antibody Testing Data (1)
TROY Antibody in Western Blot (WB)
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TROY Antibody in Western Blot (WB)
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TROY Antibody (MA5-37871) in WB

Western blot analysis of TROY in extracts of various cell lines. Samples were incubated with TROY Monoclonal antibody (Product # MA5-37871) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TROY Antibody in Western Blot (WB)
TROY Recombinant Rabbit Monoclonal Antibody (1R8Y5)

Product Details

MA5-37871

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Rat, Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

1R8Y5

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human TROY/TNFRSF19 (Q9NS68)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897791

Product Specific Information

Positive Samples: 22Rv1, Raji, U-251MG, Mouse lung, Mouse brain, Mouse spleen, Rat lung, Rat brain

Immunogen sequence: RFQKANCSAT SDAICGDCLP GFYRKTKLVG FQDMECVPCG DPPPPYEPHC ASKVNLVKIA STASSPRDTA LAAVICSALA TVLLALLILC VIYCKRQFME K

Target Information

Tumor necrosis factor receptor superfamily member 19, commonly known as TROY, is a gene located on chromosome 1p36.22 that encodes a member of the tumor necrosis factor receptor (TNFR) superfamily. TROY is expressed in the nervous system, skin, and various tissues, where it plays a role in regulating cell apoptosis, inflammation, and development. As a receptor, TROY interacts with ligands and other signaling molecules to modulate pathways involved in cell survival, differentiation, and immune responses. In the context of the nervous system, TROY has been implicated in axonal outgrowth and regeneration, particularly influencing signaling pathways related to neural development and repair. Additionally, TROY has been studied in cancer research due to its potential role in tumor growth and progression, making it a candidate for therapeutic targeting. Its involvement in diverse biological processes highlights its significance in maintaining cellular homeostasis and its potential as a therapeutic target in neurobiology and oncology.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Toxicity and JNK inducer; TRADE; Tumor necrosis factor receptor superfamily member 19; tumor necrosis factor receptor superfamily, member 19

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Gene Aliases: AL023044; AW123854; RGD1564996; TAJ; TAJ-ALPHA; TNFRSF19; TRADE; TROY; UNQ1888/PRO4333

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UniProt ID: (Human) Q9NS68, (Mouse) Q9JLL3

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Entrez Gene ID: (Human) 55504, (Rat) 290300, (Mouse) 29820

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Function(s)
receptor activity tumor necrosis factor-activated receptor activity
Process(es)
hair follicle development positive regulation of I-kappaB kinase/NF-kappaB signaling apoptotic process JNK cascade tissue development tumor necrosis factor-mediated signaling pathway positive regulation of JNK cascade
It has to be done as per old AB suggested Products section.
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