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  • TRIM24 Antibodies

Invitrogen

TRIM24 Polyclonal Antibody

View all (38) TRIM24 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite TRIM24 Polyclonal Antibody

  • Antibody Testing Data (5)
TRIM24 Antibody in Immunocytochemistry (ICC/IF)
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TRIM24 Antibody in Immunocytochemistry (ICC/IF)
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FIGURE: 1 / 5

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TRIM24 Antibody (PA5-111177) in ICC/IF

Immunofluorescent analysis of TRIM24 in human cell line U-251 MG using TRIM24 Polyclonal Antibody (Product # PA5-111177). Staining shows localization to nucleoplasm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TRIM24 Antibody in Immunocytochemistry (ICC/IF)
TRIM24 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TRIM24 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TRIM24 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TRIM24 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
TRIM24 Polyclonal Antibody

Product Details

PA5-111177

Applications
Tested Dilution
Publications

Western Blot (WB)

0.04-0.4 µg/mL
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL
-
Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human TRIM24. Recombinant protein control fragment (Product #RP-100381).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856587

Product Specific Information

Immunogen sequence: SSPVGGSYNL PSLPDIDCSS TIMLDNIVRK DTNIDHGQPR PPSNRTVQSP NSSVPSPGLA GPVTMTSVHP PIRSPSA

Target Information

The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: E3 ubiquitin-protein ligase TRIM24; RING finger protein 82; RING-type E3 ubiquitin transferase TIF1-alpha; TIF1-alpha; Transcription intermediary factor 1-alpha; transcriptional intermediary factor 1; tripartite motif-containing 24; Tripartite motif-containing protein 24

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Gene Aliases: hTIF1; PTC6; RNF82; TF1A; TIF1; TIF1A; TIF1ALPHA; TRIM24

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UniProt ID: (Human) O15164

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Entrez Gene ID: (Human) 8805

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Function(s)
p53 binding chromatin binding transcription coactivator activity protein tyrosine kinase activity ubiquitin-protein transferase activity receptor binding protein binding zinc ion binding ligase activity ligand-dependent nuclear receptor binding estrogen response element binding methylated histone binding sequence-specific DNA binding ubiquitin protein ligase activity lysine-acetylated histone binding
Process(es)
transcription from RNA polymerase II promoter negative regulation of cell proliferation protein ubiquitination peptidyl-tyrosine phosphorylation protein catabolic process regulation of protein stability regulation of apoptotic process negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated protein autophosphorylation calcium ion homeostasis regulation of vitamin D receptor signaling pathway cellular response to estrogen stimulus regulation of signal transduction by p53 class mediator
It has to be done as per old AB suggested Products section.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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