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  • TRF1 Antibodies

Invitrogen

TRF1 Polyclonal Antibody

View all (17) TRF1 antibodies

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Datasheet
Protocols
Questions & Answers

Cite TRF1 Polyclonal Antibody

  • Antibody Testing Data (1)
TRF1 Antibody in Western Blot (WB)
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TRF1 Antibody in Western Blot (WB)
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TRF1 Antibody (PA5-86084) in WB

Western blot analysis of TRF1 in Lane 1: HEK293T whole cell lysate, Lane 2: Raw264.7 whole cell lysate, Lane 3: H9C2 whole cell lysate. Sample was incubated with TRF1 polyclonal antibody (Product # PA5-86084) using a 1:500 dilution. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TRF1 Antibody in Western Blot (WB)
TRF1 Polyclonal Antibody

Product Details

PA5-86084

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide, corresponding to amino acids 200-250 of Human TRF1.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2802884

Product Specific Information

Purity is > 95% by SDS-PAGE.

Target Information

This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: FLJ41416; NIMA-interacting protein 2; Telomeric protein Pin2/TRF1; telomeric repeat binding factor (NIMA-interacting) 1; telomeric repeat binding factor 1; Telomeric repeat-binding factor 1; TTAGGG repeat-binding factor 1

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Gene Aliases: hTRF1-AS; PIN2; t-TRF1; TERF1; TRBF1; TRF; TRF1

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UniProt ID: (Human) P54274, (Mouse) P70371

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Entrez Gene ID: (Human) 7013, (Rat) 297758, (Mouse) 21749

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Function(s)
DNA binding double-stranded telomeric DNA binding telomerase activity protein binding DNA binding, bending telomeric DNA binding protein homodimerization activity ubiquitin binding G-rich strand telomeric DNA binding molecular_function chromatin binding microtubule binding protein heterodimerization activity
Process(es)
telomere maintenance telomere maintenance via telomerase mitotic nuclear division negative regulation of DNA replication telomere capping telomeric loop formation negative regulation of telomere maintenance via telomerase negative regulation of telomere maintenance via semi-conservative replication response to drug meiotic telomere clustering cell division negative regulation of telomerase activity positive regulation of telosome assembly negative regulation of establishment of protein localization to telomere negative regulation of establishment of RNA localization to telomere negative regulation of establishment of macromolecular complex localization to telomere G2/M transition of mitotic cell cycle obsolete age-dependent telomere shortening mitotic spindle assembly checkpoint obsolete telomere maintenance via telomere shortening positive regulation of microtubule polymerization positive regulation of apoptotic process positive regulation of mitotic nuclear division positive regulation of mitotic cell cycle protein homooligomerization cell cycle
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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