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  • Primary Antibodies ›
  • TRF1 Antibodies

Invitrogen

TRF1 Polyclonal Antibody

1 Reference
View all (17) TRF1 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Cite TRF1 Polyclonal Antibody

  • Antibody Testing Data (3)
TRF1 Antibody in Immunocytochemistry (ICC/IF)
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TRF1 Antibody in Immunocytochemistry (ICC/IF)
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TRF1 Antibody (PA5-28423) in ICC/IF

TRF1 Polyclonal Antibody detects TRF1 protein at spindle by immunofluorescent analysis. Sample: U2OS cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: TRF1 stained by TRF1 Polyclonal Antibody (Product # PA5-28423) diluted at 1:500. Blue: Fluoroshield with DAPI . {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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TRF1 Antibody in Immunocytochemistry (ICC/IF)
TRF1 Antibody in Immunocytochemistry (ICC/IF)
TRF1 Antibody in Western Blot (WB)
TRF1 Polyclonal Antibody

Product Details

PA5-28423

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:3,000
-

Immunohistochemistry (Frozen) (IHC (F))

-
View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:100-1:1,000
-
Product Specifications

Species Reactivity

Human

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TRF1. The exact sequence is proprietary.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7, with 10% glycerol

Contains

0.01% thimerosal

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2545899

Product Specific Information

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: FLJ41416; NIMA-interacting protein 2; Telomeric protein Pin2/TRF1; telomeric repeat binding factor (NIMA-interacting) 1; Telomeric repeat-binding factor 1; TTAGGG repeat-binding factor 1

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Gene Aliases: hTRF1-AS; PIN2; t-TRF1; TERF1; TRBF1; TRF; TRF1

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UniProt ID: (Human) P54274

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Entrez Gene ID: (Human) 7013

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Function(s)
DNA binding double-stranded telomeric DNA binding telomerase activity protein binding DNA binding, bending telomeric DNA binding protein homodimerization activity ubiquitin binding G-rich strand telomeric DNA binding
Process(es)
telomere maintenance telomere maintenance via telomerase mitotic nuclear division negative regulation of DNA replication telomere capping telomeric loop formation negative regulation of telomere maintenance via telomerase negative regulation of telomere maintenance via semi-conservative replication response to drug meiotic telomere clustering cell division negative regulation of telomerase activity positive regulation of telosome assembly negative regulation of establishment of protein localization to telomere negative regulation of establishment of RNA localization to telomere negative regulation of establishment of macromolecular complex localization to telomere
It has to be done as per old AB suggested Products section.
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Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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